achievement (collect 50 items in a single run), X-Lax - Spawns a pool of slippery brown creep beneath Isaac, Experimental Pill - Increases one random stat and decreases another random stat. No longer reduces your devil/angel room chances when used, * item room, treasure room, item room pool, the lost item pool, bomb, tnt, clock, red, When used, causes all enemies in the current room to run away from Isaac in fear for 5 seconds. box, yellow, grey, When used, converts 1 soul/black heart into 1 red heart container, This item will take from your soul hearts first, REPENTANCE - Converter now only costs one soul heart to use (previously costed two), * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket, When used, this item will spawn a set of items or consumables based on which chapter you are currently on, Basement 1: 2 Soul hearts. UNLOCK: Unlock this item by defeating Ultra Greed as Apollyon, At the start of each new hostile room, you have a 20% chance to gain a random charmed familiar which will fight for you, The charmed enemy has its own health bar and will die if it takes enough damage, Charmed enemies persist between each room and floor for as long as they stay alive, Allows you to have more than one charmed familiar at a time if you can keep them alive, * pokemon, phone, black, green, blue, gps, Every time one of your tears hits an enemy, it has a chance to start bleeding, which will cause it to take damage every 5 seconds, The bleed damage dealt by BackStabber is based on how quickly an enemy is moving (faster enemies take more damage), Damaging enemies from behind gives the bleed effect a 100% chance to apply, While an enemy bleeds, they leave behind creep that damages other enemies, The tear that inflicts the bleed effect also deals double damage, *, knife, dagger, red, heart, silver, knife, When used, Sharp Straw will deal damage to all enemies in the room, The damage dealt is equal to Isaac's current tear damage plus 10% of the enemy's max health, Every time this item deals damage, it has a 15% chance to drop 1/2 red hearts, REPENTANCE - Sharp Straw is now only able to generate half red hearts (previously, it generated half soul hearts if the player had no heart containers), A razor blade orbital that deals contact damage and applies the bleeding status effect to enemies and bosses, which will cause them to take damage every 5 seconds, The contact damage dealt by Mom's Razor is based on how quickly an enemy is moving (faster enemies take more damage), Its speed is not affected by the Guardian Angel item, An eye orbital that shoots tears that deal 3.5 damage and deals 2 contact damage per tick to enemies, The damage dealt by this orbital does not scale with damage upgrades, REPENTANCE - Bloodshot Eye now blocks enemy shots, has increased shot speed and rate of fire, and now only shoots when lined up with enemies, When used, spawns a charmed random white delirium version of a boss, that will fight for you and kill other enemies for the rest of the current room, Possible bosses spawned include most bosses in the game, Some bosses' effects can harm Isaac. If you get hit while Cursed eye is a solid black colour you are guaranteed to be teleported to another random room on the floor. Caves 2: 1 Boss Item + 2 Soul Hearts, Depths 1: 4 Soul hearts. The room doors will open if only frozen enemies remain, UNLOCK: Unlock this trinket by defeating challenge #41 (Pica Run), Every time you kill an enemy you get an invincibility shield for 1 second, While shielded, each enemy killed adds +1 seconds to the duration, UNLOCK: Unlock this trinket by defeating challenge #37 (Bloody Mary), Teleports the player to the first room of the current floor, There is a guaranteed Fool card in the Depths 2, if you bomb the skull with an X on it. devil room pool, devil deal, paper, pink, brown, isaac, Gives a 50% chance to not take damage from projectiles, * golden chest pool, gold chest pool, secret room pool, item room, treasure room, item room pool, effect for 10 seconds. * secret room pool, item room, treasure room, item room pool, 25, grey, gray, silver, devil pool, devil room pool, devil deal, Converts most negative pills into their positive counterparts, e.g. The effect is weaker than normal runes. The creep deals 2 damage per tick while enemies stand in it, Lazarus' revived form (Lazarus II) respawns with this item, * item room, treasure room, item room pool, blood drop, red blood, drip, Gives Isaac a guaranteed devil or angel room on every floor that they can appear, even if you have already beaten the boss and it didn't show up originally, Taking the Goat Head (or any other item) in a Devil Deal bars you from encountering Angel Rooms naturally. Based on the Steam Workshop mod created by Jean-Alphonse, UNLOCK: Unlock this item by opening 20 locked chests, *, mr me!, Mr Meeseeks, rick and morty, brown, chest, szechuan sauce, mister me, Grants a prism orbital with a large orbital radius, Isaac's tears that pass through the prism split into four multi-colored tears, Does not deal contact damage to enemies that it passes over, Added as part of the Afterbirth+ Booster Pack #3. smile, lil' brimstone, Prevents Isaac from taking any damage, but instead summons a familiar heart that follows you around. - When used, shoots an Ipecac explosive shot. If used with Brimstone you have a 100% chance to fire a laser out the back of your head, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, Based on the Steam Workshop mod created by by Scayze and Ashkait, *, bloody, paper, script, white, red, toilet paper, seven seals. It can spawn familiars you haven't unlocked yet! Go to Steam > settings > controller > Desktop configuration I was having issues with trying to make a new one so I just edited the "Disabled" configuration into what you see on the image. Returning back through the mirror door returns you back to normal again. UNLOCK: Unlock this item by beating the Isaac boss with Azazel, * the satanic bible library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, the lost item pool, pentagram, star, grey, gray, red, When used, fires a 4 way brimstone laser in all cardinal directions, dealing a lot of damage to any enemies, Laser damage does not scale with your damage stat - its a fixed 10 damage per tick for 20 ticks (200 total per use), Has a chance to drop after you beat Krampus, If you get close enough to an enemy that has a large hitbox, you can hit it with 2 of the laser beams, allowing you to deal more damage, UNLOCK: Unlock this item by beating Krampus (Krampus is unlocked by taking 20 devil deal items), *, horns, grey, gray, white, red, dead, tongue, krampus head, When used, farts on nearby enemies and knocks them backwards away from Isaac, Allows you to reflect projectiles away from Isaac, REPENTANCE - Butter Bean now knocks back enemies and projectiles with significantly more force. Every 40 seconds spent in the same room since last activating, when the timer displays 00, 20 or 40 seconds, a shield triggers, nullifying all types of damage for 10 seconds, As soon as Isaac has half a red heart or more, this item deactivates, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Lazarus, While firing tears this item gives you a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac, The evil eye shots will be destroyed if they come into contact with enemies or obstacles, UNLOCK: Unlock this item by beating Greed Mode with Cain, Each time Isaac kills an enemy, you get a temporary +0.5 damage up which lasts for the current room, Each subsequent kill will stack further damage up to a maximum of +5 Damage Up after 10 kills, This item is the same principle as the Bloody Lust item from the original flash game, REPENTANCE - Added to the Devil Room pool, UNLOCK: Unlock this item by beating Greed Mode with Samson, Item Pool: Item Room, Devil Room, Greed Mode Item Room, After taking enough damage you will gain a permanent demon familiar, Possible familiars include: Dark Bum, Demon Baby, Leech, Lil' Brimstone, Succubus, Incubus, Lil Abaddon, Twisted Pair. Charge time increased to 4 (from 2), UNLOCK: Unlock this item by dying 100 times, * item room, treasure room, item room pool, grey, gray, Holding the active item button will deplete the charge bar. Isaac's touch now petrifies enemies, turning them to gold for a few seconds. by doing a victory lap), UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon, *, grey, gray, brown, orange, steam, coffee, tea, drink, cup, When used, Compost doubles up the current number of blue flies and spiders you have, When picked up, Compost will also destroy every consumable on the ground in the current room and turn each of them into a blue fly or blue spider, If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider, When used, this item will distort all the sprites and music, rotating graphics 90 degrees and translating them diagonally up/left, while leaving the hitbox in the same place. Using the Red Key near it will spawn a red room, This room will randomly choose from many types, including (but not limited to) any regular room from that floor, treasure rooms, curse rooms, devil rooms, angel rooms, I AM ERROR rooms and more, In rooms with multiple door outlines, the closest one will be opened, Attempting to create a room outside the maximum boundary (13 x 13 rooms) of the map will take you to an I AM ERROR room. ), UNLOCK: Unlock this item by beating Blue Womb (Hush) with Cain, Gives Isaac a familiar golden Censer which creates a huge aura of light that slows down any enemies inside it, UNLOCK: Unlock this item by beating Greed Mode with Maggy, A familiar beggar similar to Bum Friend that follows Isaac and collects keys, giving random chests in return, UNLOCK: Unlock this item by beating Greed Mode with Lazarus, Item Pool: Item Room, Secret Room, Key Beggar, *, grey, gray, black, face, stone, rock, baby, A bag that follows Isaac and drops a random Rune or Soul Stone every 7 or 8 rooms, UNLOCK: Unlock this item by beating the Isaac boss with Lilith, A familiar angel which follows Isaac and fires Sacred Heart tears which deal 10 damage at -25% shot speed and a reduced fire rate, Item Pool: Item Room, Angel Room, Greed Mode Angel Room, This item causes enemy projectiles to be able to hit other enemies. Also summons a blue crosshair which can be moved around freely. I don't intend in publishing it anywhere when I finish it, but I do want to know opinions . The item is between Big Chubby (473) and Plan C (475) horizontally. The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy, *, grey, silver, sword, dagger, blade, knife, Tears now have a random chance to become sticky bombs, which will attach to enemies and explode after a few seconds, The bomb explosion deals your tear damage + 60, REPENTANCE - Explosivo tears now deal damage upon impact, When picked up, drops between 1-6 random pickups on the floor, Causes all item pedestals to be chosen from a random item pool instead of the pre-defined ones which normally exist, Fixed item drops won't be replaced - e.g. This gives you his ability to fly, and the Holy Mantle effect. Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap, Greatly decreases damage (x0.33 damage multiplier), Individual tears gain random worm effects (e.g. Dessert = +1 Flat Damage, +0.2 shot speed. It rerolls enemies and pickups it comes into contact with, then despawns. Cannot be obtained and has no use for any other character, Birthright is a Shop item that has unique effects depending on what character you're playing as, This is the item Tainted Blue Baby (???) when using this mod on co op, the 2nd player activated item is invisible, it doesnt happen to the main player, i don't think any of the mods i use could collide with items on that part of the ui, but in case, what kind of mods could?, when i use this mod but the no hud version, the activated item does appear . This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. (6 full hearts to fully charge), Unless fully charged, hearts picked up are consumed by the Alabaster Box, instead of being added to your life total. mario, cartridge, nes, grey, gray, orange, When used, rerolls each item you currently own into another item room pool item and any pedestal items and pickups in the room, Has the combined uses of the D4, D6 and D20, REPENTANCE - Full run reroll effects (such as D4) are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by beating Boss Rush with The Lost, * item room, treasure room, item room pool, deathstar, death star, dice pip, white, circle, sphere, When used, the D4 re-rolls each item you currently have into another random item from the same item pool, If you have an item with no room pool (e.g. - Speeds up all enemies for the rest of the room. 3 keys = 25% chance. Void tears that touch enemies will spawn Big Horn, who appears and grabs them, instantly killing that enemy, The chance to for each tear to become a void tear is affected by your luck stat and at +15 Luck it will activate 20% of the time, Isaac also grows a horn on his head, which causes you to deal contact damage to enemies by running into them (this effect deals base damage of 3.5 per tick), Void tears from this item can also destroy blue/purple fires, spiked blocks and stone grimaces, When used, will spawn a fly turret that doesn't move and fires tears at nearby enemies, The fly's bullets deal 3.5 damage each and do not scale with your own damage stat. as Bethany, Gives you a random syringe effect every room, The effect can be The Virus, Roid Rage, Speed Ball, Experimental Treatment, Synthoil, Euthanasia or Growth Hormones, Placed bombs explode after 0.66 seconds instead of the usual 1.5 seconds, This was called Exploded Firecracker in Antibirth, Farts produced by Isaac or familiars will be twice as large, Chance for enemies to burn when entering a room, The chance for this effect to activate is effected by your Luck stat, This includes key blocks and golden chests, Pickups left on current floor will appear in the starting room of the next floor, up to a maximum of 4 pickups, Active items will be rerolled upon using them, Using with Book of Virtues will only reroll the item the book is holding, Has no effect with Notched Axe due to how its durability works, UNLOCK: Unlock this trinket by defeating Mother as Eden, Random luck-based tear effects have an extra chance of occurring, The additional chance is effectively +3 Luck Up, Picking up red hearts now has a high chance to spawn 1-4 blue attack spiders, instead of giving you health back, This effect also works while fully healed, giving a guaranteed chance of getting spiders, While missing any red health the chance for spiders is less, Works for characters that don't use red health, which always gives you spiders, Hearts in Shops can be converted into spiders for free, Gives your familiars improved rate of fire while held, In Antibirth this trinket was called Song of the Siren, UNLOCK: Unlock this trinket by bombing the skull left by The Siren boss after her death, While held at the start of each floor, this trinket spawns four wisp familiar orbitals around Isaac, These wisps are the same as the ones created by the Book of Virtues item, UNLOCK: Unlock this trinket by beating the Boss Rush as Bethany, Your active item no longer gains charges, but battery drops become much more common, UNLOCK: Unlock this trinket by blowing up 10 Battery Beggars, Tears that miss enemies will redirect themselves and travel 90 degrees towards enemies, Tears must be roughly 2 tiles or closer to activate this effect, +10 Luck while held, but the trinket is destroyed when damage is taken, Blood donation machines, Curse Rooms and Sacrifice Rooms wont destroy it, Taking a hit and activating Holy Mantle won't destroy it, Can be dropped in order to avoid breaking it, This trinket is automatically given to you after clearing 3 bosses without taking damage, Treasure Rooms are replaced with Red Treasure Rooms, which contain a deal with the devil in place of a regular item pedestal, If an item room has not yet been entered, it can be transformed to either a regular or Red Treasure Room by picking up or dropping this trinket before entering, Does not affect the mirrored treasure room in Downpour II, UNLOCK: Unlock this trinket by defeating Mother as Azazel, Every time you pick up a coin, you have a small chance to gain 1 bar of charge on your active item, The chance for this effect to happen is 1/6th of the value of the coin picked up, Can only activate once per coin collected, In Antibirth this trinket was called Electric Penny, UNLOCK: Unlock this trinket by donating to a battery beggar until he pays out with an item 5 times, While held, your familiars will now orbit around Isaac instead of following behind him, Activates your active item just before damage would be taken, It doesn't activate for free - the charges are used up as normal if this effect activates. When used, this card drops all of your hearts (including non-red hearts), coins, keys and bombs on the floor, This effect is done in the most efficient way possible - e.g. white, red, pink, When used, slows down all enemies in the current room and their projectiles for about 8 seconds, * item room, treasure room, item room pool, hour glass, hourglass, egg timer, sandbrown, glass, A familiar which follows Isaac around and shoots blood tears that deal 5 damage, The tears appear red but have no additional damage, Sister Maggy fires tears at a rate of 1 tear per second, REPENTANCE - Sister Maggy's tear damage has been increased to 5 (from 3.5), to match its original Flash damage, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red, dead, baby, Isaac's tears are replaced with a laser that has unlimited range and can only fire at right angles, Lasers travel through enemies but not obstacles in the room, Synergizes with most items that affect how many tears you fire (20/20, Mutant Spider etc.)
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